<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Simon,L.S.</style></author><author><style face="normal" font="default" size="100%">Strand,C.V.</style></author><author><style face="normal" font="default" size="100%">Boers,M.</style></author><author><style face="normal" font="default" size="100%">Brooks,P.M.</style></author><author><style face="normal" font="default" size="100%">Tugwell,P.S.</style></author><author><style face="normal" font="default" size="100%">Bombardier,C.</style></author><author><style face="normal" font="default" size="100%">Fries,J.F.</style></author><author><style face="normal" font="default" size="100%">Henry,D.</style></author><author><style face="normal" font="default" size="100%">Goldkind,L.</style></author><author><style face="normal" font="default" size="100%">Guyatt,G.</style></author><author><style face="normal" font="default" size="100%">Laupacis,A.</style></author><author><style face="normal" font="default" size="100%">Lynd,L.</style></author><author><style face="normal" font="default" size="100%">Macdonald,T.</style></author><author><style face="normal" font="default" size="100%">Mamdani,M.</style></author><author><style face="normal" font="default" size="100%">Moore,A.</style></author><author><style face="normal" font="default" size="100%">Saag,K.S.</style></author><author><style face="normal" font="default" size="100%">Silman,A.J.</style></author><author><style face="normal" font="default" size="100%">Stevens,R.</style></author><author><style face="normal" font="default" size="100%">Tyndall,A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">How to ascertain drug safety in the context of benefit. Controversies and concerns</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Rheumatology</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J.Rheumatol.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">health care</style></keyword><keyword><style  face="normal" font="default" size="100%">musculoskeletal disorders</style></keyword><keyword><style  face="normal" font="default" size="100%">outcome</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2009/09//</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">36</style></volume><pages><style face="normal" font="default" size="100%">2114 - 2121</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">There is great concern about clearly defining benefit and risk in the context of both drug development and clinical practice. In view of this pressure, the OMERACT Executive identified the need to bring together clinical trialists, pharmacoepidemiologists, clinicians, clinical epidemiologists, statistical experts, and regulatory representatives to discuss different approaches to define risk and perhaps improved ways to express it. Each attendee spoke on a given topic and the group was charged to consider the issue of risk in the context of formally posed questions. This article provides a summary of the presentations and outlines the discussions that followed</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue><notes><style face="normal" font="default" size="100%">DA - 20090909 IS - 0315-162X (Print) LA - eng PT - Journal Article RN - 0 (Antirheumatic Agents) SB - IM</style></notes><custom1><style face="normal" font="default" size="100%">&lt;a href=&quot;/biblio/custom1/clinical-treatment&quot;&gt;clinical treatment&lt;/a&gt;</style></custom1></record></records></xml>
